In this neighborhood, the street grid runs parallel and perpendicular to Market Street. The name SOMA refers to "South of Market" and denotes both a comparatively large district of the city, as well as a much smaller neighborhood. The SOMA contains several smaller neighborhoods such as South Park, Yerba Buena, South Beach, and Financial District South, and overlaps with several others, notably Mission Bay, and the Mission District.
A major transformation of the neighborhood was planned during the 2000s with the Transbay Terminal Replacement Project, which broke ground in August 2010, and is planned to be open by 2017. In addition, new highrise residential projects like One Rincon Hill, 300 Spear Street, and Millennium Tower are transforming the San Francisco skyline and the character of this neighborhood. Source: Wikipedia
Fun Fact: In 1847, surveyor Jasper O'Farrell was commissioned to extend the boundaries of the pueblo San Francisco in a southerly direction by creating a new subdivision. At the time, the streets of San Francisco were aligned (approximately) with the compass points, running north to south, or east to west. O'Farrell decided that the streets in the new subdivision should run parallel with or perpendicular to the only existing road in the area, Mission Road (later Mission Street), and thus be aligned with the half-points of the compass, i.e., northeast to southwest, and northwest to southeast. Finally, O'Farrell created "a grand promenade" linking the old pueblo with the new subdivision, Market Street. Source: Wikipedia